Tumor inhibiting [1,2-bis(fluorophenyl)ethylenediamine]platinum(II) complexes. Part IV: Biological evaluation--in vivo studies on the P 388 leukemia.

نویسندگان

  • H Reile
  • T Spruss
  • G Bernhardt
  • R Müller
  • R Gust
  • H Schönenberger
چکیده

In experiments on the P 388 leukemia of the mouse diaqua-[l Z-bis-(fluorophenyl)ethylenediamine]platinum(II) sulfates and nitrates show a strong antitumor activity irrespective of the position of the fluorine atom (ortho, mts or para) and of their configuration (R,R/S,S or R,S). Tumorhemmende [1,2-Bis(fluorphenyl)ethylendlamin]platin(II) Komplexe, 4. Teil: Biologische Priifung I n vivo Studien an der P 388 Leukiimie

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عنوان ژورنال:
  • Archiv der Pharmazie

دوره 324 7  شماره 

صفحات  -

تاریخ انتشار 1991